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Various algorithmic and statistical approaches have been proposed to uncover functionally coherent network motifs consisting of sets of genes that may occur as compensatory pathways (called Between Pathway Modules, or BPMs) in a high-throughput S. Cerevisiae genetic interaction network. We extend our previous Local-Cut/Genecentric method to also make use of a spectral clustering of the physical interaction network, and uncover some interesting new fault-tolerant modules. 

Remote scientific collaborations have been pivotal in generating scientific discoveries and breakthroughs that accelerate research in many fields. Emerging VR applications for remote work, which utilize commercially available head-mounted displays (HMDs), offer the promise to enhance collaboration, through spatial and embodied experiences. However, there is little evidence on how professionals in general, and scientists in particular, could use existing commercial VR applications to support their cognitive and creative collaborative processes while exploring real-world data as part of day-to-day collaborative work. In this paper, we present findings from an empirical study with 14 coral reef scientists, examining how they chose to utilize available resources in existing virtual environments for their ongoing data-driven collaborative research. We shed light on scientists’ data organization practices, identify affordances unique to VR for supporting cognition in a collaborative setting, and highlight design requirements for supporting cognitive and creative collaboration processes in future tools.